Endocrine Abstracts

Introduction: Dapagliflozin is sodium-glucose co-transporter receptor 2 (SGLT2) inhibitor that is recently discovered an oral antidiabetic (OAD) agent that improves glycemic control by increasing the renal excretion of glucose. Vulvovaginal candidiasis (VVC) is the infection of the vaginal vestibuler area. We present a case of VVC accompanied by use of dapagliflozin.Case: A-48-year-old woman who had T2DM since 8 years was admitted to the endocrinology cl...

Introduction: High level of Parathormone (PTH) impair bone health by increasing the risk of fracture. The aim is to determine the threshold value of PTH elevation to accompany deficiency or failure of Vit D. This may be an important parameter in assessing bone metabolism in clinical practice.Material and method: 931 patients who were referred to the endocrinology clinic were retrospectively studied and 880 patients diagnosed with Vit D deficiency include...

Aim: Thyroid hormones have many effects on the cardiovascular system. May studies have showed that apparent or subclinical hypothyroidism increase the risk of hypertension hyperlipidemia and so lead to atherosclerosis susceptibility. This risk can be reduced by treatment. But, studies on the relationship between thyroid function tests and cardiovascular risk in euthyroid subjects are contradictory. This study was designed to investigate the effect of TSH, free T3, f...

Aim: There are studies showing that Hashimoto’s thyroiditis (HT) progresses more rapidly, thyroid echogenicity is lower and thyroid autoantibodies are higher titer positive in immunoglobulin G4 (IGg4) positive patients.But a small number of studies that do not support this data have also been published.We planned this study to evaluate the findings of IgG4 (+) Hashimoto’s thyroiditis cases.Materials and methods: New diagnosis without treatment ...

Introduction: Hyperthyroidism is the condition that occurs due to excessive release of thyroid hormone by the thyroid gland. Anti-thyroid drugs are usually the first choice of the treatment but surgery and radioactive iodine can also be used in treatment of hyperthyroidism. Plasmapheresis is a rapid and effective treatment option in cases where immediate euthyroidism is needed to be obtained due to complications of thyrotoxicosis and major side effects of antithyroid drugs.</p...

Introduction: Autoimmune polyglandular syndrome type 2 (APS2) is the most common form of the polyglandular failure syndromes. Seventy-five percent of cases occur in women. Adrenal insufficiency is the principal manifestation occurs with autoimmune thyroid disease or type I diabetes mellitus. The incidence of autoimmune thyroid diseases in APS2 is 70%; 30% Hashimoto’s thyroiditis, 20% non toxic goiter, 20% hypertyroidism is seen. We will discuss about a patient with APS2, ...